- Short Communication
- Open Access
Percutaneous closure of accidentally subclavian artery catheterization: time to change first line approach?
CVIR Endovascular volume 5, Article number: 23 (2022)
To present our experience and provide a literature review dissertation about the use of a suture-mediated percutaneous closure device (Perclose Proglide -PP- Abbott Vascular Inc., Santa Clara, CA, USA) to achieve hemostasis for unintended subclavian arterial catheterization during central venous line placement.
Materials & methods
Since October 2020, we have successfully treated four consecutive patients with a central venous catheter (8 to 12 French) in the subclavian artery. In each patient, we released a PP, monitoring its efficacy by performing a subclavian angiogram and placing, as a rescue strategy, an 8 mm balloon catheter near the entry point of the misplaced catheter. Primary outcome is technical and clinical success. Technical success is defined as absence of bleeding signs at completion angiography, while clinical success is a composite endpoint defined as absence of hematoma, hemoglobin loss at 12 and 24 h, and absence of procedure-related reintervention (due to vessel stenosis, pseudoaneurysm or distal embolization).
Technical success was obtained in 75% of cases. In one patient a mild extravasation was resolved after 3 min of balloon catheter inflation. No early complications were observed for all patients.
PP showed a safe and effective therapeutic option in case of unintentional arterial cannulation. It can be considered as first-line strategy, as it does not preclude the possibility to use other endovascular approaches in case of vascular closure device failure.
Despite the improvement of ultrasound guided catheterization, the incidence of unintended arterial puncture is still estimated to range between 2% and 4.5%, and large-bore catheter cannulation in 0.1 – 0.5% of patients. (Lorenzo et al. 2020; Ezaru et al. 2009; Brass et al. 2015). Subclavian artery is more frequently involved compared to carotid artery (2.7% vs. 1% respectively). Manual compression is often ineffective to achieve hemostasis due to the anatomical artery position (Park et al. 2016). Open surgery is burdened by high invasiveness and important blood loss. Endovascular use of covered stent-graft is a valuable alternative to open surgery but presents the risk of vertebral artery occlusion. Recently, vascular closure devices (VCD) have been used to treat the damaged vessel. This study aims to present a single center experience with Perclose Proglide (PP) (Abbott Vascular, Santa Clara, USA).
Materials & methods
Since October 2020, first approach to treat unintentional artery cannulations of the upper extremity was managed with PP. All patients were preventively studied with CT angiography to confirm the site of arterial puncture and its relationship with contiguous structures and arterial branches. A doppler US was also performed to exclude the presence of arteriovenous fistulas.
All the procedures are performed in hybrid room under local anesthesia. The upper chest, neck, and right groin or right radial area are draped in a sterile fashion. Primary vascular access was ultrasound-guided through the common femoral artery (Radifocus Introducer 7Fr, Terumo, Japan) or radial artery (Prelude Ideal 7 F Merit, USA).
A preliminary angiography is performed to localize central venous line entrance into the artery wall. An 8-mm diameter occlusion balloon catheter is then advanced close to the damaged artery for hemostasis in case of VCD failure. The venous catheter is withdrawn on a 0.035-inch guidewire (Radifocus M guidewire standard type, Terumo, Japan) and a PP is inserted and deployed.
Completion angiography is performed to confirm the success of the procedure (Fig. 1). In case of persistent bleeding, a second device can be positioned, or, alternatively, a balloon inflated or stent graft deployed through the primary access.
Primary outcome is technical and clinical success. Technical success is defined as absence of bleeding signs at completion angiography, while clinical success is a composite endpoint defined as absence of hematoma, hemoglobin loss at 12 and 24 h, and absence of procedure-related reintervention (due to vessel stenosis, pseudoaneurysm or distal embolization).
Secondary outcomes are procedural time, fluoroscopy time, and amount of iodinate contrast medium used.
All patients were informed that the device used for hemostasis was not designed/tested for the specific purpose and gave their consent to treatment.
Four consecutive patients were treated for unintentional subclavian artery cannulation (3 males, average age 65.5 years). Main characteristics of each procedure are depicted in Table 1. Central venous catheter used ranged between 8 and 12 French caliber.
Technical success was obtained in 75% of cases. Patient 2 presented a mild extravasation after PP deployment that resolved after 3 min of balloon catheter inflation. No early complications were observed for all patients. Mean procedural time was 39 ± 18 min, mean dose area product (DAP) was 203 ± 55 Gycm2, mean iodine contrast medium used was 50 ± 22 ml. Clinical success was achieved in all patients.
VCD has revolutionized percutaneous access hemostasis, offering a safe and effective alternative to manual compression (Makris et al. 2017). However, none of the VCDs has indication for subclavian artery.
Our limited experience with PP to achieve hemostasis in unintentional subclavian artery catheterization shows promising results with 100% of clinical success, high technical success, no need for stenting or surgical conversion, and with a small amount of iodinate contrast medium, procedural time and radiogenic exposure.
Similar experiences have been published in literature. Dornbos et al. (2019) reported 50 cases of VCD in both subclavian and brachiocephalic artery injuries with successful primary hemostasis in 94% of cases and no complications with PP. The 3 cases (6%) of failure requiring covered stenting were observed with the previous Perclose, Angioseal (St. Jude Medical, USA) and 1 unspecified VCD. 2 complications have been reported including formation of a pseudoaneurysm (StarClose, Abbott Vascular) (Stellmes et al. 2014) and vessel occlusion (Angioseal) (Sharma et al. 2008). Dornbos et al. (2019). Makris et al. (2017) reported that VCD appears to be safe and effective for the management of iatrogenic thoraco-cervical vascular injuries.
In our opinion, the advantage of PP device is double: the hemostasis is achieved with exclusively extravasal material and, in case of initial failure, the presence of the guide wire allows a second device deployment. Moreover, in case of PP failure, this technique does not preclude the use of a different endovascular approach (stent-graft).
Another advantage of VCD compared to the use of stent graft or surgical repair is the cost-effectiveness; a PP device is 10 times less expensive than a stent graft and costs of surgical hemostasis can be considered even higher.
To our knowledge, 10 cases of accidental subclavian artery puncture resolved with the placement of a PP have been reported (Table 2). In all cases, full technical success was achieved (with no need for stenting or surgical revision) without postoperative complications.
Although the PP has reduced profiles compared to the previous Perclose or the Prostar XL, the depth of the puncture site makes the descent of the suture thread rather difficult, even with the knot pusher (Berti et al. 2020). Due to the difficult positioning, the possibility of device failure and/or complications remains potentially high: We believe that the safest endovascular approach is possible when, prior to the deployment of a VCD, a balloon catheter is positioned on the entry site of the artery to tamponade eventual lesser vessel injury after VCD deployment, and to use it as a pre-existent way for exchange in case it is needed to place a covered stent. Although Lorenzo et al. (2020), we believe that bedside ultrasound-guided placement of PP should be limited to extremely critical and non-transportable patients.
PP showed a safe and effective therapeutic option in case of unintentional arterial cannulation. It can be considered as a first-line strategy, as it does not preclude the possibility to use other endovascular approaches in case of VCD failure.
Availability of data and materials
The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.
Vascular closure devices
Berti S, Bedogni F, Giordano A, Petronio AS, Iadanza A, Bartorelli AL, et al (2020) Efficacy and safety of proglide versus prostar XL vascular closure devices in transcatheter aortic valve replacement: The rispeva registry. J Am Heart Assoc 9
Brass P, Hellmich M, Kolodziej L, Schick G, Smith AF (2015) Ultrasound guidance versus anatomical landmarks for internal jugular vein catheterization. Cochrane Database Syst Rev
Chivate RS, Kulkarni SS, Shetty NS, Polnaya AM, Gala KB, Patel PG (2016) Percutaneous repair of iatrogenic subclavian artery injury by suture-mediated closure device. Indian J Radiol Imaging 26
Dornbos DL, Nimjee SM, Smith TP (2019) Inadvertent Arterial Placement of Central Venous Catheters: Systematic Review and Guidelines for Treatment. J Vasc Interv Radiol
Ezaru CS, Mangione MP, Oravitz TM, Ibinson JW, Bjerke RJ (2009) Eliminating arterial injury during central venous catheterization using manometry. Anesth Analg 109
Jahromi BS, Tummala RP, Levy EI (2009) Inadvertent subclavian artery catheter placement complicated by stroke: Endovascular management and review. Catheter Cardiovasc Interv 73
Lorenzo JF, Rey JV, Arquillo IL, Encisa de Sá JM (2020) Off-label use of Proglide percutaneous closure device in iatrogenic arterial catheterizations: Our experience. Vascular
Makris GC, Patel R, Little M, Tyrrell C, Sutcliffe J, Allouni K, et al (2017) Closure Devices for Iatrogenic Thoraco-Cervical Vascular Injuries. Cardiovasc Intervent Radiol 40
Park TK, Yang JH, Choi SH (2016) Endovascular repair using suture-mediated closure devices and balloon tamponade following inadvertent subclavian artery catheterization with large-caliber hemodialysis catheter. Korean Circ J 46
Sharma M, Sakhuja R, Teitel D, Boyle A (2008) Percutaneous arterial closure for inadvertent cannulation of the subclavian artery - A call for caution. J Invasive Cardiol 20
Stellmes A, Diehm N, Book M, Schmidli J, Do D do, Gralla J (2014) Arterial closure devices for treatment of inadvertent large-caliber catheter insertion into the subclavian or carotid artery: A case series of five patients. J Cardiothorac Vasc Anesth 28
Yoon DY, Annambhotla S, Resnick SA, Eskandari MK, Rodriguez HE (2015) Inadvertent Arterial Placement of Central Venous Catheters: Diagnostic and Therapeutic Strategies. Ann Vasc Surg 29
No specific grants from any funding agency in the public, commercial, or not-for-profit sectors were received for this study.
Ethics approval and consent to participate
All procedures were performed in accordance with the ethical standards of the institutional and/or national research committees and the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.
Consent for publication
Written informed consent was obtained from the patients for publication of this case report and any accompanying images.
The authors declare that they have no competing interests.
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
About this article
Cite this article
Discalzi, A., Maglia, C., Ciferri, F. et al. Percutaneous closure of accidentally subclavian artery catheterization: time to change first line approach?. CVIR Endovasc 5, 23 (2022). https://doi.org/10.1186/s42155-022-00300-7
- Subclavian artery injuries
- Central venous catheterisation
- Endovascular repair
- Vascular closure device, Perclose Proglide