Table 4 Interaction effect on the association of fracking versus conventional balloon angioplasty with 1-year restenosis
Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|
HR (95% CI) | P-value | HR (95% CI) | P-value | |
Age ≥ 80, y | 0.37 (0.13–1.03) | 0.056 | 0.39 (0.14–1.08) | 0.071 |
Diabetes mellitus | 2.03 (0.68–6.07) | 0.207 | ||
Chronic kidney disease | 0.82 (0.33–2.01) | 0.666 | ||
Hemodialysis | 1.59 (0.63–4.01) | 0.330 | ||
Chronic limb-threatening ischemia | 1.31 (0.47–3.60) | 0.604 | ||
Lesions only in CFA region | 0.72 (0.30–1.74) | 0.467 | ||
No deep femoral artery lesions | 0.51 (0.21–1.24) | 0.138 | ||
Chronic total occlusion | 1.64 (0.60–4.52) | 0.337 | ||
Focal lesion | 1.30 (0.54–3.15) | 0.555 | ||
De novo lesion | 1.08 (0.25–4.66) | 0.919 | ||
Distal reference vessel diameter (per 1.0 mm) | 0.90 (0.52–1.54) | 0.693 | ||
Lesion length (per 1.0 mm) | 0.99 (0.97–1.03) | 0.919 | ||
PACSS grade | 0.88 (0.60–1.30) | 0.528 | ||
Bilateral calcified lesions | 0.77 (0.32–1.84) | 0.551 | ||
No below-the-knee artery run-off | 0.91 (0.21–3.94) | 0.903 | ||
Noncompliant balloon use | 1.68 (0.49–5.74) | 0.407 | ||
Scoring/Cutting balloon use | 0.90 (0.36–2.25) | 0.815 | ||
Drug coating balloon use | 0.74 (0.28–1.93) | 0.538 | ||
Residual stenosis | 1.01 (0.99–1.04) | 0.229 | ||
Dissection, none to mild | 1.14 (0.38–3.41) | 0.819 | ||
Calcium angle ≥180–360° by IVUS analysis | 1.21 (0.46–3.15) | 0.694 | ||
Postoperative MLA (per 1.0 mm2) | 0.85 (0.78–0.93) | < 0.001 | 0.78 (0.67–0.91) | < 0.001 |
Acute gain (per 1.0 mm2) | 0.93 (0.86–0.99) | 0.038 | 1.10 (0.96–1.27) | 0.162 |