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Table 2 Lesion and procedure characteristics

From: Fracking compared to conventional balloon angioplasty alone for calcified common femoral artery lesions using intravascular ultrasound analysis: 12-month results

Variables

Total

n = 67

Fracking

n = 32

Balloon

n = 35

P-value

Rutherford classification

3.3 ± 0.9

3.1 ± 0.8

3.4 ± 1.0

0.143

Chronic limb-threatening ischemia

16 (24)

5 (16)

9 (31)

0.134

Preoperative ankle-brachial index

0.45 ± 0.32

0.52 ± 0.29

0.39 ± 0.34

0.095

De novo lesion

59 (88)

29 (91)

30 (86)

0.543

Lesions only in CFA region

33 (49)

22 (69)

11 (31)

0.002

Deep femoral artery disease

17 (26)

7 (22)

10 (29)

0.536

Focal lesion

27 (40)

13 (41)

14 (40)

0.959

Preoperative stenosis (%)

92.0 ± 9.6

96.5 ± 6.4

87.9 ± 10.2

< 0.001

Proximal reference vessel diameter (mm)

6.3 ± 0.8

6.4 ± 0.9

6.2 ± 0.8

0.344

Distal reference vessel diameter (mm)

5.6 ± 0.8

5.8 ± 0.9

5.5 ± 0.7

0.165

Lesion length (mm)

38.7 ± 14.3

38.4 ± 14.6

38.8 ± 14.3

0.906

Chronic total occlusion

11 (16)

4 (12)

7 (20)

0.415

length (mm)

30.0 ± 8.9

27.5 ± 12.6

31.4 ± 6.9

0.512

PACSS grade

2.4 ± 1.1

3.0 ± 1.0

1.94 ± 1.0

< 0.001

    1, 2

21 (31), 8 (12)

5 (16), 1 (3)

16 (46), 7 (20)

0.007, 0.034

    3, 4

25 (37), 13 (19)

15 (47), 11 (34)

10 (29), 2 (6)

0.125, 0.003

Bilateral calcium

38 (57)

26 (81)

12 (34)

< 0.001

Below-the-knee arterial run-off

1.7 ± 0.9

1.9 ± 0.9

1.5 ± 0.9

0.086

Noncompliant balloon use

39 (58)

25 (78)

27 (77)

0.925

Scoring and cutting balloon use

45 (67)

22 (69)

23 (66)

0.795

Drug-coated balloon use

23 (34)

11 (34)

12 (34)

0.994

Postprocedural dissection, none to mild

50 (75)

21 (66)

29 (83)

0.109

Procedure time (min)

66.9 ± 50.7

56.0 ± 24.0

76.9 ± 65.2

0.092

Contrast dose (ml)

132.9 ± 55.7

121.4 ± 36.3

143.4 ± 67.7

0.107

Radiation time (min)

39.2 ± 35.7

25.5 ± 13.8

51.6 ± 44.3

0.002

Number of Fracking

2.4 ± 0.8

Fracking procedure time (min)

10.1 ± 3.8

Postoperative stenosis (%)

24.2 ± 16.8

19.5 ± 12.3

28.6 ± 19.3

0.027

Postoperative ankle-brachial index

0.88 ± 0.27

0.99 ± 0.20

0.78 ± 0.28

< 0.001

IVUS examination

 Proximal reference vessel area (mm2)

55.0 ± 15.1

54.8 ± 14.8

55.1 ± 15.6

0.947

 Lesion vessel area (mm2)

47.6 ± 11.6

46.0 ± 11.5

49.0 ± 11.6

0.302

 Preoperative MLA (mm2)

5.8 ± 3.4

5.7 ± 3.1

5.9 ± 3.7

0.839

 Preoperative plaque burden (%)

87 ± 8

86 ± 8

87 ± 8

0.706

 Distal reference vessel area (mm2)

40.2 ± 14.4

37.3 ± 15.1

42.9 ± 13.3

0.110

 Calcium angle ≥180–360°

43 (74)

26 (81)

17 (49)

0.005

 Postoperative MLA (mm2)

17.2 ± 6.0

22.1 ± 4.0

12.7 ± 3.3

< 0.001

 Acute gain (mm2)

11.2 ± 6.8

16.4 ± 4.8

6.8 ± 4.4

< 0.001

 Postoperative plaque burden (%)

61 ± 17

49 ± 16

73 ± 9

< 0.001

  1. Continuous variables are indicated as mean ± standard deviation. Categorical variables are expressed as the counts (percentage)
  2. Abbreviations: CFA common femoral artery, IVUS intravascular ultrasound, MLA minimum lumen area, PACSS Peripheral Artery Calcium Scoring System